Combine Darwin and Hershes ideas.
I have stayed away from S&D because last time I used it, it tried to make me buy it... and I don't buy things listed as "freeware" on downlaoad.com (popular downloads.)
In other news... None of those programs search any of your drives except your host drive (C: in most cases) and thus enable certain spywares to continue existance.
For Example:
I have two run32dll files going. All I remember is that this particluar spyware uses a lot of memory; sucky, but I cannot get rid of it becuase I cannot find where it is hidden on my other drive...... so I am debating a full format, re-install, etc. On top of that, it interferes with my CD-Burner, so backing up things is not happeneing either.*sigh* I guess I'll fix it this weekend.